“Teach the ignorant as much as you can; society is culpable in not providing a free education for all and it must answer for the night which it produces. If the soul is left in darkness sins will be committed. The guilty one is not he who commits the sin, but he who causes the darkness.”—
“Suddenly there was a great burst of light through the Darkness. The light spread out and where it touched the Darkness the Darkness disappeared. The light spread until the patch of Dark Thing had vanished, and there was only a gentle shining, and through the shining came the stars, clear and pure.”—Madeleine L’Engle, A Wrinkle in Time (via pluiefine)
“The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents. We live on a placid island of ignorance in the midst of black seas of infinity, and it was not meant that we should voyage far. The sciences, each straining in its own direction, have hitherto harmed us little; but some day the piecing together of dissociated knowledge will open up such terrifying vistas of reality, and of our frightful position therein, that we shall either go mad from the revelation or flee from the deadly light into the peace and safety of a new dark age.”—H.P. Lovecraft, The Call of Cthulhu (via lunautical)
“Home is behind, the world ahead,
And there are many paths to tread
Through shadows to the edge of night,
Until the stars are all alight.
Then world behind and home ahead,
We’ll wander back and home to bed.
Mist and twilight, cloud and shade,
Away shall fade! Away shall fade!”—J.R.R. Tolkien, The Fellowship of the Ring (via alfsaga)
“To love at all is to be vulnerable. Love anything and your heart will be wrung and possibly broken. If you want to make sure of keeping it intact you must give it to no one, not even an animal. Wrap it carefully round with hobbies and little luxuries; avoid all entanglements. Lock it up safe in the casket or coffin of your selfishness. But in that casket, safe, dark, motionless, airless, it will change. It will not be broken; it will become unbreakable, impenetrable, irredeemable. To love is to be vulnerable.”—C.S. Lewis, The Four Loves (via thebluearrow)
“How ridiculous that water ran out of your eyes when your heart hurt. Tragic heroines in books tended to be amazingly beautiful. Not a word about swollen eyes or a red nose. ‘Crying always gives me a red nose’, thought Elinor. ‘I expect that’s why I’ll never be in any book’.”—Inkdeath, Cornelia Funke (via draha)
“a woman who had vanished, not only out of the family and the house but out of life too, into an edifice like Bluebeard’s and there transmogrified into a mask looking back with passive and hopeless grief upon the irrevocable world”—William Faulkner, Absalom, Absalom! (via beneathbixbybridge)
Male contraceptive pill is a step closer after gene discovery
A contraceptive pill for men which works by preventing sperm development could result from the discovery of a new gene, scientists have said.
The gene, which is active in the testes, controls the final stages of sperm development. Blocking it would result in temporary infertility, without permanently damaging a man’s sperm-making machinery, the researchers said.
One of the greatest problems associated with developing a male contraceptive is knowing how to block the immense sperm-producing factories of the testes with near 100 per cent reliability but without long-term damage.
Several attempts at making a contraceptive based on blocking testosterone have run into difficulties, not least because of adverse side-effects such as irritability, tiredness and loss of sex drive.
But scientists believe the discovery of a gene called Katnal1 could provide a potential solution given its pivotal role in the last stages of sperm development.
When the gene is blocked, the testes continue to make sperm, but only ineffective, immature sperm are released, said Lee Smith of Edinburgh University. “The effects of such a drug would be reversible, because Katnal1 only affects sperm cells in the later stages of development, so it would not hinder the overall ability to produce sperm,” he said.
The scientists, funded by the Medical Research Council, discovered Katnal1’s role by analysing the DNA of infertile male mice that had suffered mutations to their genetic material.
Further research, published in online journal PloS Genetics, revealed Katnal1 controls the fine network of microscopic tubes that supply nutrients to the final developmental stages of sperm cells just before they are ready for release.
When Katnal1 is blocked, the microscopic tubules break down earlier than they should, which arrests sperm development. The result is that the sperm cells are released in an immature state, making them incapable of fertilising an egg cell, Dr Smith said. “Although other research is being carried out into non-hormonal male contraceptives, identification of a gene that controls sperm production is a unique and significant step forward,” he said. But he added it will still take years before potential drugs can be tested on men.
“We all start out knowing magic. We are born with whirlwinds, forest fires, and comets inside us. We are born able to sing to birds and read the clouds and see our destiny in grains of sand. But then we get it the magic educated right out of our souls. We get it churched out, spanked out, washed out, and combed out. We get put on the straight and narrow path and told to be responsible. Told to act our age. Told to grow up, for God’s sake. And you know why we were told that? Because the people doing the telling were afraid of our wildness and youth, and because the magic we knew made them ashamed and sad of what they’d allowed to wither in themselves.”—Robert R. McCammon (via internal-acceptance-movement)
“God does not play dice with the universe; He plays an ineffable game of his own devising, which might be compared, from the perspective of any of the other players, to being involved in an obscure and complex version of poker in a pitch dark room, with blank cards, for infinite stakes, with a dealer who won’t tell you the rules, and who smiles all the time.”—Good Omens - Terry Pratchett and Neil Gaiman (via spetharrific)
“No, I don’t give them names, but I can tell one from another by their shapes and patterns. And besides, there wouldn’t be much point in giving them names: they die so quickly. These people are your nameless friends for just a little while. I come here everyday, say hello to the butterflies, and talk about things with them. When the time comes though, they just quietly go off and disappear. I’m sure it means they’ve died, but I can never find their bodies. They don’t leave any trace behind. It’s as if they’ve been absorbed by the air. They’re dainty little creatures that hardly exist at all: they come out of nowhere, search quietly for a few, limited things, and disappear into nothingness again, perhaps to some other world.”—Haruki Murakami, 1Q84 (via rudeteenager)
To write the best version of whatever it is you are working on, you’ve got to find some way to care about it. For some folks, this is a grade or a paycheck. For others, it will be the idea or issue itself. In my experience, caring about a grade or a paycheck does not…
Lol half of your followers are on tumblrdatinggame(.)com
This isn’t a question. It is a statement. A statement that is totally irrelevant to my life or this blog. So I don’t know why you think I care. I’m not even sure why I’m replying to this. Never contact me again if this is all you post.
“You smile at the absurdity of your dream and feel at the same time that the tissue of those absurdities contains some thought, but a thought that is real, something that belongs to your true life, something that exists and has always existed in your heart; it is as if your dream has told you something new, prophetic, awaited; your impression is strong, it is joyful or tormenting, but what it is and what has been told you—all that you can neither comprehend nor recall.”—Fyodor Dostoyevsky, The Idiot (1869)
“A computer chatted to itself in alarm as it noticed an airlock open and close itself for no apparent reason.
This was because Reason was in fact out to lunch.”—Douglas Adams, The Hitchhiker’s Guide to the Galaxy (via litreferential)
“I admire him greatly. What I admire the most in him is that he despises us all; all writers. Perhaps a more accurate description is that he treats us, other writers, as completely empty space. You could argue that from time to time, he praises Maupassant, or Kuprin, or Semenov, or myself. But why does he praise us? It is simple: it’s because he looks at us as if we were children. Our short stories, or even our novels, all are child’s play in comparison with his works. However, Shakespeare … For him, the reason is different. Shakespeare irritates him because he is a grown-up writer, and does not write in the way that Tolstoy does.”—Chekhov on Tolstoy (via noconsensusonaname)